Most donors rest for 24 hours after the egg retrieval in Mexico, and most go back to their normal schedule the following day. Other donors experience more painful menstrual-like symptoms (cramps/bloating/headaches) that can last up to a week.
In very rare cases donors may have a severe reaction to fertility drugs that will require additional medical treatment or hospitalization.
There can occasionally be light spotting 24-48 hours after the procedure. This is not something to worry about as it can be due to scarring in the uterus.