Endometrial Co-Culture


The process of the endometrial co-culture allows embryos to develop in an environment similar to the Uterus before the transfer. There are a variety of patients who might be suitable for endometrial co-culture. In cases of previous slow embryo development, a stop in development or bad quality embryos, endometrial co-culture can be an option.

One week after ovulation, a sample is taken from the uterine lining and multiplied in the laboratory. This takes about 1 to 3 weeks. The cells that have been sampled are those from the tissue into which the embryos would adhere to.

During the cultivation the embryo development is being observed and the liquid nourishing the cells is renewed every 48 hours. This process can therefore only take place in well staffed and equipped laboratory.

The cells multiply and build a single-layered surface. Here the embryos nest themselves in and develop further. Inactivated and filtered blood of the patient is used as a serum in the co-culture process. 

Patients who have the co-culture done usually proceed with the blastocyst transfer, i.e. the embryo transfer takes place on the 4th, 5th, or 6th day.









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